Publications

1: Vedantam G, Kochanowsky J, Lindsey J, Mallozzi M, Roxas JL, Adamson C, Anwar F, Clark A, Claus-Walker R, Mansoor A, McQuade R, Monasky RC, Ramamurthy S, Roxas B, Viswanathan VK. An Engineered Synthetic Biologic Protects Against Clostridium difficile Infection. Front Microbiol. 2018 Sep 5;9:2080. doi: 10.3389/fmicb.2018.02080. eCollection 2018. PubMed PMID: 30233548; PubMed Central PMCID: PMC6134020.

 

2: Roxas JL, Vedantam G, Viswanathan VK. Epithelial maturity influences EPEC-induced desmosomal alterations. Gut Microbes. 2018 Sep 5:1-5. doi: 10.1080/19490976.2018.1506669. [Epub ahead of print] PubMed PMID: 30183504.

 

3: Roxas JL, Monasky RC, Roxas B, Agellon AB, Mansoor A, Kaper JB, Vedantam G, Viswanathan VK. Enteropathogenic Escherichia coli EspH-Mediated Rho GTPase Inhibition Results in Desmosomal Perturbations. Cell Mol Gastroenterol Hepatol. 2018 Apr 27;6(2):163-180. doi: 10.1016/j.jcmgh.2018.04.007. eCollection 2018. PubMed PMID: 30003123; PubMed Central PMCID: PMC6039986.

 

4: Roxas JL, Viswanathan VK. Modulation of Intestinal Paracellular Transport by Bacterial Pathogens. Compr Physiol. 2018 Mar 25;8(2):823-842. doi: 10.1002/cphy.c170034. PubMed PMID: 29687905.

 

5: Soavelomandroso AP, Gaudin F, Hoys S, Nicolas V, Vedantam G, Janoir C, Bouttier S. Biofilm Structures in a Mono-Associated Mouse Model of Clostridium difficile Infection. Front Microbiol. 2017 Oct 25;8:2086. doi: 10.3389/fmicb.2017.02086. eCollection 2017. PubMed PMID: 29118745; PubMed Central PMCID: PMC5661025.

 

6: Chu M, Mallozzi M, Roxas B, Bertolo L, Monteiro MA, Agellon A, Viswanathan VK, Vedantam G. A Clostridium difficile Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence. PLoS Pathog. 2016 Oct 14;12(10):e1005946. doi: 10.1371/journal.ppat.1005946. eCollection 2016 Oct. PubMed PMID: 27741317; PubMed Central PMCID: PMC5065235.

 

7: Kullin B, Brock T, Rajabally N, Anwar F, Vedantam G, Reid S, Abratt V. Characterisation of Clostridium difficile strains isolated from Groote Schuur Hospital, Cape Town, South Africa. Eur J Clin Microbiol Infect Dis. 2016 Oct;35(10):1709-18. doi: 10.1007/s10096-016-2717-6. Epub 2016 Jul 27. PubMed

PMID: 27465145.

 

8: Pantaléon V, Soavelomandroso AP, Bouttier S, Briandet R, Roxas B, Chu M, Collignon A, Janoir C, Vedantam G, Candela T. The Clostridium difficile Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties. PLoS One. 2015 Apr 29;10(4):e0124971. doi: 10.1371/journal.pone.0124971. eCollection 2015. PubMed PMID: 25922949; PubMed Central PMCID: PMC4414356.

 

9: Wilbur JS, Byrd W, Ramamurthy S, Ledvina HE, Khirfan K, Riggs MW, Boedeker EC, Vedantam G, Viswanathan VK. The secreted effector protein EspZ is essential for virulence of rabbit enteropathogenic Escherichia coli. Infect Immun. 2015 Mar;83(3):1139-49. doi: 10.1128/IAI.02876-14. Epub 2015 Jan 5. PubMed PMID: 25561713; PubMed Central PMCID: PMC4333479.

 

10: Viswanathan VK. The trendy microbes. Gut Microbes. 2014 Jul 1;5(4):439-40. doi: 10.4161/gmic.36381. Epub 2014 Sep 15. PubMed PMID: 25222378.

 

11: Viswanathan VK. Muramyl dipeptide: Not just another brick in the wall. Gut Microbes. 2014 May-Jun;5(3):275-6. doi: 10.4161/gmic.32181. Epub 2014 Jul 28. PubMed PMID: 25068259; PubMed Central PMCID: PMC4153763.

 

12: Roxas JL, Ryan K, Vedantam G, Viswanathan VK. Enteropathogenic Escherichia coli dynamically regulates EGFR signaling in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 1;307(3):G374-80. doi: 10.1152/ajpgi.00312.2013. Epub 2014 Jun 5. PubMed PMID: 24904077; PubMed Central PMCID: PMC4121633.

 

13: Viswanathan VK. Memories of a virulent past. Gut Microbes. 2014 Mar-Apr;5(2):143-5. doi: 10.4161/gmic.28340. Epub 2014 Feb 27. PubMed PMID: 24637797.

 

14: Viswanathan VK. Off-label abuse of antibiotics by bacteria. Gut Microbes. 2014 Jan-Feb;5(1):3-4. doi: 10.4161/gmic.28027. Epub 2014 Jan 29. PubMed PMID: 24637595; PubMed Central PMCID: PMC4049933.

 

15: Merrigan MM, Venugopal A, Roxas JL, Anwar F, Mallozzi M, Roxas B, Gerding DN, Viswanathan VK, Vedantam G. Surface-layer protein A (SlpA) is a major contributor to host-cell adherence of Clostridium difficile. PLoS One. 2013 Nov 12;8(11):e78404. doi: 10.1371/journal.pone.0078404. eCollection 2013. PubMed PMID: 24265687; PubMed Central PMCID: PMC3827033.

 

16: Viswanathan V. The meddling microbes midst our medicines. Gut Microbes. 2013 Sep-Oct;4(5):359-60. doi: 10.4161/gmic.26250. Epub 2013 Aug 22. PubMed PMID: 23969979; PubMed Central PMCID: PMC3839979.

 

17: Viswanathan VK. Shigella takes the temperature. Gut Microbes. 2013 Jul-Aug;4(4):267-8. doi: 10.4161/gmic.25726. Epub 2013 Jul 11. PubMed PMID: 23851363; PubMed Central PMCID: PMC3744510.

 

18: Monteiro MA, Ma Z, Bertolo L, Jiao Y, Arroyo L, Hodgins D, Mallozzi M, Vedantam G, Sagermann M, Sundsmo J, Chow H. Carbohydrate-based Clostridium difficile vaccines. Expert Rev Vaccines. 2013 Apr;12(4):421-31. doi: 10.1586/erv.13.9. Review. PubMed PMID: 23560922.

 

19: Viswanathan VK. Oh what tangled webs we weave…. Gut Microbes. 2013 May-Jun;4(3):179-80. doi: 10.4161/gmic.24388. Epub 2013 Mar 21. PubMed PMID: 23519061; PubMed Central PMCID: PMC3669162.

 

20: Viswanathan VK. Sensing bacteria, without bitterness? Gut Microbes. 2013 Mar-Apr;4(2):91-3. doi: 10.4161/gmic.23776. Epub 2013 Feb 4. Review. PubMed PMID: 23380647; PubMed Central PMCID: PMC3595082.

 

21: Viswanathan VK. Sizing up microbes. Gut Microbes. 2012 Nov-Dec;3(6):483-4. doi: 10.4161/gmic.22637. PubMed PMID: 23117415; PubMed Central PMCID: PMC3495784.

 

22: Viswanathan VK. Sizing up microbes. Gut Microbes. 2012 Oct 31;3(6). [Epub ahead of print] PubMed PMID: 23114834.

 

23: McQuade R, Roxas B, Viswanathan VK, Vedantam G. Clostridium difficile clinical isolates exhibit variable susceptibility and proteome alterations upon exposure to mammalian cationic antimicrobial peptides. Anaerobe. 2012 Dec;18(6):614-20. doi: 10.1016/j.anaerobe.2012.09.004. Epub 2012 Sep 24. PubMed PMID: 23017940.

 

24: Vedantam G, Viswanathan VK. Spirochaetes and their twisted ways. Gut Microbes. 2012 Sep-Oct;3(5):399-400. Epub 2012 Sep 1. Review. PubMed PMID: 22976336.

 

25: Roxas JL, Wilbur JS, Zhang X, Martinez G, Vedantam G, Viswanathan VK. The enteropathogenic Escherichia coli-secreted protein EspZ inhibits host cell apoptosis. Infect Immun. 2012 Nov;80(11):3850-7. doi: 10.1128/IAI.00335-12. Epub 2012 Aug 20. PubMed PMID: 22907816; PubMed Central PMCID: PMC3486051.

 

26: Vedantam G, Viswanathan VK. Naming names: eponyms and biological history. Gut Microbes. 2012 May-Jun;3(3):173-5. doi: 10.4161/gmic.20454. Epub 2012 May 1. PubMed PMID: 22572826; PubMed Central PMCID: PMC3427210.

 

27: Vedantam G, Clark A, Chu M, McQuade R, Mallozzi M, Viswanathan VK. Clostridium difficile infection: toxins and non-toxin virulence factors, and their contributions to disease establishment and host response. Gut Microbes. 2012 Mar-Apr;3(2):121-34. doi: 10.4161/gmic.19399. Epub 2012 Mar 1. Review. PubMed PMID: 22555464; PubMed Central PMCID: PMC3370945.

 

28: Bertolo L, Boncheff AG, Ma Z, Chen YH, Wakeford T, Friendship RM, Rosseau J, Weese JS, Chu M, Mallozzi M, Vedantam G, Monteiro MA. Clostridium difficile carbohydrates: glucan in spores, PSII common antigen in cells, immunogenicity of PSII in swine and synthesis of a dual C. difficile-ETEC conjugate vaccine. Carbohydr Res. 2012 Jun 1;354:79-86. doi: 10.1016/j.carres.2012.03.032. Epub 2012 Apr 2. PubMed PMID: 22533919.

 

29: Nguyen M, Vedantam G. Mobile genetic elements in the genus Bacteroides, and their mechanism(s) of dissemination. Mob Genet Elements. 2011 Sep;1(3):187-196. Epub 2011 Sep 1. PubMed PMID: 22479685; PubMed Central PMCID: PMC3312300.

 

30: Vedantam G, Viswanathan VK. Leptin signaling protects the gut from Entamoeba histolytica infection. Gut Microbes. 2012 Jan-Feb;3(1):2-3. doi: 10.4161/gmic.19424. Epub 2012 Jan 1. Review. PubMed PMID: 22356851.

 

31: Chatfield CH, Mulhern BJ, Viswanathan VK, Cianciotto NP. The major facilitator superfamily-type protein LbtC promotes the utilization of the legiobactin siderophore by Legionella pneumophila. Microbiology. 2012 Mar;158(Pt 3):721-35. doi: 10.1099/mic.0.055533-0. Epub 2011 Dec 8. PubMed PMID: 22160401; PubMed Central PMCID: PMC3352117.

 

32: Siddiqui F, O'Connor JR, Nagaro K, Cheknis A, Sambol SP, Vedantam G, Gerding DN, Johnson S. Vaccination with parenteral toxoid B protects hamsters against lethal challenge with toxin A-negative, toxin B-positive Clostridium difficile but does not prevent colonization. J Infect Dis. 2012 Jan 1;205(1):128-33. doi: 10.1093/infdis/jir688. Epub 2011 Nov 28. PubMed PMID: 22124129.

 

33: Viswanathan VK. Bacteriophages: the ultimate agents of change. Gut Microbes. 2011 Jul-Aug;2(4):209-10. doi: 10.4161/gmic.2.4.17123. Epub 2011 Jul 1. PubMed PMID: 21983065.

 

34: Vedantam G, Viswanathan VK. Unlocking the gates to inflammatory bowel disease: the role of Enterococcus faecalis gelatinase. Gastroenterology. 2011 Sep;141(3):795-8. doi: 10.1053/j.gastro.2011.07.022. Epub 2011 Jul 23. PubMed PMID: 21791208.

 

35: Vedantam G, Viswanathan VK. A more perfect union. Gut Microbes. 2011 May-Jun;2(3):125-6. Epub 2011 May 1. PubMed PMID: 21637032.

 

36: Viswanathan VK. Of cabbages and kings. Gut Microbes. 2011 Mar-Apr;2(2):67-8. Epub 2011 Mar 1. PubMed PMID: 21637022.

 

37: Viswanathan VK. Self portraits. Gut microbiology. Gut Microbes. 2010 Nov-Dec;1(6):357-8. doi: 10.4161/gmic.1.6.13907. PubMed PMID: 21468215; PubMed Central PMCID: PMC3056098.

 

38: Viswanathan VK. Fascinating science, compelling cause. Gut Microbes. 2010 Jan;1(1):3. PubMed PMID: 21327111; PubMed Central PMCID: PMC3035141.

 

39: Viswanathan VK. Tossed salads. Gut Microbes. 2010 Sep;1(5):291-292. Epub 2010 Jul 6. PubMed PMID: 21327036; PubMed Central PMCID: PMC3023612.

 

40: Viswanathan VK, Mallozzi M, Vedantam G. Clostridium difficile infection: An overview of the disease and its pathogenesis, epidemiology and interventions. Gut Microbes. 2010 Jul;1(4):234-242. Epub 2010 Jun 16. PubMed PMID: 21327030; PubMed Central PMCID: PMC3023605.

 

41: Viswanathan VK. Eating in, eating out. Gut Microbes. 2010 Jul;1(4):207-208. Epub 2010 May 10. PubMed PMID: 21327026; PubMed Central PMCID: PMC3023601.

 

42: Viswanathan VK. What is black and white and a puzzle all over? Gut Microbes. 2010 May-Jun;1(3):129-30. doi: 10.4161/gmic.1.3.11673. Epub 2010 Feb 16. PubMed PMID: 21327019; PubMed Central PMCID: PMC3023592.

 

43: Viswanathan VK. Humor me. Gut Microbes. 2010 Mar;1(2):75-76. Epub 2009 Dec 31. PubMed PMID: 21326912; PubMed Central PMCID: PMC3023582.

 

44: Coursodon CF, Trinh HT, Mallozzi M, Vedantam G, Glock RD, Songer JG. Clostridium perfringens alpha toxin is produced in the intestines of broiler chicks inoculated with an alpha toxin mutant. Anaerobe. 2010 Dec;16(6):614-7. doi: 10.1016/j.anaerobe.2010.09.006. Epub 2010 Oct 8. PubMed PMID: 20934524.

 

45: Merrigan M, Venugopal A, Mallozzi M, Roxas B, Viswanathan VK, Johnson S, Gerding DN, Vedantam G. Human hypervirulent Clostridium difficile strains exhibit increased sporulation as well as robust toxin production. J Bacteriol. 2010 Oct;192(19):4904-11. doi: 10.1128/JB.00445-10. Epub 2010 Jul 30. PubMed PMID: 20675495; PubMed Central PMCID: PMC2944552.

 

46: Mallozzi M, Viswanathan VK, Vedantam G. Spore-forming Bacilli and Clostridia in human disease. Future Microbiol. 2010 Jul;5(7):1109-23. doi: 10.2217/fmb.10.60. Review. PubMed PMID: 20632809.

 

47: Lepp D, Roxas B, Parreira VR, Marri PR, Rosey EL, Gong J, Songer JG, Vedantam G, Prescott JF. Identification of novel pathogenicity loci in Clostridium perfringens strains that cause avian necrotic enteritis. PLoS One. 2010 May 24;5(5):e10795. doi: 10.1371/journal.pone.0010795. Erratum in: PLoS One. 2010;5(6). doi: 10.1371/annotation/501e5656-71ac-420f-a194-80141f6381e5. PubMed PMID: 20532244; PubMed Central PMCID: PMC2879425.