Vedantam Laboratory Publications

Vedantam: Publications

  1. Vedantam G, Kochanowsky J, Lindsey J, Mallozzi M, Roxas JL, Adamson C, Anwar F, Clark A, Claus-Walker R, Mansoor A, McQuade R, Monasky RC, Ramamurthy S, Roxas B, Viswanathan VK. An Engineered Synthetic Biologic Protects Against Clostridium difficile Infection. Front Microbiol. 2018 Sep 5;9:2080. doi: 10.3389/fmicb.2018.02080. eCollection 2018. PubMed PMID: 30233548; PubMed Central PMCID: PMC6134020.
     
  2. Soavelomandroso AP, Gaudin F, Hoys S, Nicolas V, Vedantam G, Janoir C, Bouttier S. Biofilm Structures in a Mono-Associated Mouse Model of Clostridium difficile Infection. Front Microbiol. 2017 Oct 25;8:2086. doi: 10.3389/fmicb.2017.02086. eCollection 2017. PubMed PMID: 29118745; PubMed Central PMCID: PMC5661025.

  3. Chu M, Mallozzi M, Roxas B, Bertolo L, Monteiro MA, Agellon A, Viswanathan VK, Vedantam G. A Clostridium difficile Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence. PLoS Pathog. 2016 Oct 14;12(10):e1005946. doi: 10.1371/journal.ppat.1005946. eCollection 2016 Oct. PubMed PMID: 27741317; PubMed Central PMCID: PMC5065235.

  4. Kullin B, Brock T, Rajabally N, Anwar F, Vedantam G, Reid S, Abratt V. Characterisation of Clostridium difficile strains isolated from Groote Schuur Hospital, Cape Town, South Africa. Eur J Clin Microbiol Infect Dis. 2016 Oct;35(10):1709-18. doi: 10.1007/s10096-016-2717-6. Epub 2016 Jul 27. PubMed PMID: 27465145.

  5. Pantaléon V, Soavelomandroso AP, Bouttier S, Briandet R, Roxas B, Chu M, Collignon A, Janoir C, Vedantam G, Candela T. The Clostridium difficile Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties. PLoS One. 2015 Apr 29;10(4):e0124971. doi: 10.1371/journal.pone.0124971. eCollection 2015. PubMed PMID: 25922949; PubMed Central PMCID: PMC4414356.

  6. Merrigan MM, Venugopal A, Roxas JL, Anwar F, Mallozzi M, Roxas B, Gerding DN, Viswanathan VK, Vedantam G. Surface-layer protein A (SlpA) is a major contributor to host-cell adherence of Clostridium difficile. PLoS One. 2013 Nov 12;8(11):e78404. doi: 10.1371/journal.pone.0078404. eCollection 2013. PubMed PMID: 24265687; PubMed Central PMCID: PMC3827033.

  7. Monteiro MA, Ma Z, Bertolo L, Jiao Y, Arroyo L, Hodgins D, Mallozzi M, Vedantam G, Sagermann M, Sundsmo J, Chow H. Carbohydrate-based Clostridium difficile vaccines. Expert Rev Vaccines. 2013 Apr;12(4):421-31. doi: 10.1586/erv.13.9. Review. PubMed PMID: 23560922.

  8. McQuade R, Roxas B, Viswanathan VK, Vedantam GClostridium difficile clinical isolates exhibit variable susceptibility and proteome alterations upon exposure to mammalian cationic antimicrobial peptides. Anaerobe. 2012 Dec;18(6):614-20. doi: 10.1016/j.anaerobe.2012.09.004. Epub 2012 Sep 24. PubMed PMID: 23017940.

  9. Vedantam G, Clark A, Chu M, McQuade R, Mallozzi M, Viswanathan VKClostridium difficile infection: toxins and non-toxin virulence factors, and their contributions to disease establishment and host response. Gut Microbes. 2012 Mar-Apr;3(2):121-34. doi: 10.4161/gmic.19399. Epub 2012 Mar 1. Review. PubMed PMID: 22555464; PubMed Central PMCID: PMC3370945.

  10. Bertolo L, Boncheff AG, Ma Z, Chen YH, Wakeford T, Friendship RM, Rosseau J, Weese JS, Chu M, Mallozzi M, Vedantam G, Monteiro MA. Clostridium difficile carbohydrates: glucan in spores, PSII common antigen in cells, immunogenicity of PSII in swine and synthesis of a dual C. difficile-ETEC conjugate vaccine. Carbohydr Res. 2012 Jun 1;354:79-86. doi: 10.1016/j.carres.2012.03.032. Epub 2012 Apr 2. PubMed PMID: 22533919.

  11. Viswanathan VK, Mallozzi M, Vedantam GClostridium difficile infection: An overview of the disease and its pathogenesis, epidemiology and interventions. Gut Microbes. 2010 Jul;1(4):234-242. Epub 2010 Jun 16. PubMed PMID: 21327030; PubMed Central PMCID: PMC3023605.

  12. Merrigan M, Venugopal A, Mallozzi M, Roxas B, Viswanathan VK, Johnson S, Gerding DN, Vedantam G. Human hypervirulent Clostridium difficile strains exhibit increased sporulation as well as robust toxin production. J Bacteriol. 2010 Oct;192(19):4904-11. doi: 10.1128/JB.00445-10. Epub 2010 Jul 30. PubMed PMID: 20675495; PubMed Central PMCID: PMC2944552.